Products
Fixatives
0.5% stabilised aqueous solution.
Ruthenium tetroxide is very similar to osmium tetroxide and is used as an EM fixative/stain.
It gives excellent staining of saturated and unsaturated polymer materials with improved image contrast.
RuO4 also has a stabilising effect against electron beam damage of material films.
Note: penetration of ruthenium tetroxide into tissue is poor.
Store at 4 °C.
5 x 10ml ampoules.
| Art. | Description | Unit | Price | Quantity | |
|---|---|---|---|---|---|
| R1027 | Ruthenium Tetroxide | 5 x 10ml | € 541,20 |
Product Description
Several grades of fixative are available:
Practical grade which is used for general fixation:
EM grade for use in electron microscopy. It is stable for over six months, has a pH 5 – 6 and proves to be an excellent fixative for structural studies.
It should also be used in histochemical or immunological reactions.
Double distilled grade which has a very low cation concentration:
Vacuum distilled grade is purified to remove all polymerised material and has no UV absorption at 235nm. It is packed in neutral glass under nitrogen for best results with enzyme histochemistry.
Any distilled glutaraldehyde is relatively unstable and has a high risk of polymerising if it is not handled properly.
It is therefore recommended that this grade of material is only purchased for use within a 3 to 4 week period and is carefully stored at 4 °C without continued defrosting and recapping.
MSDS
 | Download Material Safety Data Sheet – AGR1009 Glutaraldehyde 25% aq soln pract |
| Download Material Safety Data Sheet – AGR1010 Glutaraldehyde 25% aq soln EM grade |
| Download Material Safety Data Sheet – AGR1011 Glutaraldehyde 25% aq soln EM grade |
 | Download Material Safety Data Sheet – AGR1012 Glutaraldehyde 25% aq soln EM grade |
| Download Material Safety Data Sheet – AGR1013, AGR1014 Glutaraldehyde 70% aq soln -double distilled |
| Download Material Safety Data Sheet – AGR1020 Glutaraldehyde 25% aq soln EM grade |
| Download Material Safety Data Sheet – AGR1310, AGR1311, AGR1312 Glutaraldehyde 25% aq soln -vacuum distilled |
| Download Material Safety Data Sheet – AGR1313, AGR1314 Glutaraldehyde 50% aq soln -vacuum distilled |
| Art. | Description | Unit | Price | Quantity | |
|---|---|---|---|---|---|
| R1009 | Glutaraldehyde 25% Practical Grade | 500ml | € 47,20 | ||
| R1010 | Glutaraldehyde 25% EM Grade | 500ml | € 70,90 | ||
| R1011 | Glutaraldehyde 25% EM Grade | 250ml | € 41,10 | ||
| R1012 | Glutaraldehyde 25% EM Grade | 100ml | € 23,00 | ||
| R1020 | Glutaraldehyde 25% EM Grade ampoule | 10 x 10ml | € 60,70 | ||
| R1013 | Glutaraldehyde 70% Double Distilled ampoule | 5ml | € 12,90 | ||
| R1014 | Glutaraldehyde 70% Double Distilled ampoule | 5ml | € 9,00 | ||
| R1310 | Glutaraldehyde 25% Vacuum Distilled | 500ml | € 261,10 | ||
| R1311 | Glutaraldehyde 25% Vacuum Distilled | 100ml | € 68,70 | ||
| R1312 | Glutaraldehyde 25% Vacuum Distilled | 10 x 10ml | € 113,90 | ||
| R1313 | Glutaraldehyde 50% Vacuum Distilled | 100ml | € 128,00 | ||
| R1314 | Glutaraldehyde 50% Vacuum Distilled | 10 x 10ml | € 189,40 |
Osmium Tetroxide, OsO4, is a useful chemical compound that finds application as a staining and fixing agent for use in electron microscopy, as well as a chemical catalyst for the synthesis of specific organic chemicals.
The chemical properties of Osmium Tetroxide are such that use and handling of the chemical is often considered daunting. Although its volatility and toxicity certainly makes it a dangerous chemical, but when following the proper procedure and taking the necessary precautions, Osmium Tetroxide can be used to its full potential with limited risk to the user.
This is more toxic than glutaraldehyde and has a higher vapour pressure. Particular care must be taken to avoid breathing the vapour or allowing it to affect the eyes. Please refer to the technical data and the MSDS.
Supplied in sealed ampoules.
Technical Note
| Download Technical Note |
MSDS
| Download Material Safety Data Sheet – AGR1015, AGR1016, AGR1017 Osmium Tetroxide |
| Download Material Safety Data Sheet – AGR1019, AGR1021, AGR1022 Osmium Tetroxide 2% solution in water |
| Download Material Safety Data Sheet – AGR1023, AGR1024 Osmium Tetroxide 4% solution in water |
| Art. | Description | Unit | Price | Quantity | |
|---|---|---|---|---|---|
| R1015 | Osmium Tetroxide ampoules | 10 x 0.1g | € 139,80 | ||
| R1016 | Osmium Tetroxide ampoules | 10 x 0.25g | € 188,90 | ||
| R1017 | Osmium Tetroxide ampoule | 1g | € 84,10 | ||
| R1019 | Osmium Tetroxide 2% Solution | 100ml | € 212,40 | ||
| R1021 | Osmium Tetroxide 2% Solution ampoules | 5 x 2ml | € 70,00 | ||
| R1022 | Osmium Tetroxide 2% Solution ampoules | 5 x 5ml | € 76,70 | ||
| R1023 | Osmium Tetroxide 4% Solution ampoules | 5 x 2ml | € 80,50 | ||
| R1024 | Osmium Tetroxide 4% Solution ampoules | 5 x 5ml | € 126,90 |
Fixative
| Art. | Description | Unit | Price | Quantity | |
|---|---|---|---|---|---|
| R1215 | Potassium Permanganate | 100g | € 23,40 |
Paraformaldehyde is polymerised formaldehyde, usually obtained as a white powder.
If mixed with water and heated, it depolymerises completely and dissolves in the water to form a solution of formaldehyde or formalin.
| Art. | Description | Unit | Price | Quantity | |
|---|---|---|---|---|---|
| R1018 | Paraformaldehyde | 500g | € 16,80 |
This is an efficient and rapid penetrant fixative when used in combination with glutaraldehyde.
Available in pre-scored ampoules, sealed under inert gas.
| Art. | Description | Unit | Price | Quantity | |
|---|---|---|---|---|---|
| R1026 | Paraformaldehyde 16% Sol methanol-free | 10 x 10ml | € 66,10 |